Meet OLADOKUN DAVID OLUWASEUN, an Academic Staff of Lagos State University.
Anaesthesia And Critical Care
Lecturer I
Anasthesia
At the Anasthesia department office
Appointment on Visitation important
| # | Certificate | School | Year |
|---|---|---|---|
| 1. | Fellowship (Anaesthesia) | National Postgraduate Medical College of Nigeria | 2017 |
Investigating Cortisol as a predictor of mortality in ICU
Mortality is high among patients admitted into the intensive care unit (ICU) due to the severity of pathologies affecting them. A global epidemiology data reported ICU mortality range of between 16·2% and 25·8%,5 with a mortality of 48.3% seen among patients being managed for sepsis.6 Patients presenting with one or more organ failure at admission has been strongly associated with increased Mortality in ICU.
Scoring systems like the APACHEII, SAPS, SOFA have been utilised to assess and predict outcomes in the ICU. Hormones play a part an individuals response to critical illness and may influence outcomes.
This study aims to assess the hormone cortisol as a predictor for mortality among patients admitted into the intensive care unit.
Objectives
1. To correlate Cortisol levels with APACHE II score in predicting mortality among the patients admitted into ICUin the study.
2. To investigateassess whether combining cortisol levels with APACHE II scores improves the accuracy of mortality prediction compared to APACHE II scores alone.
3. To determine the cut-off level of cortisol associated with mortality among ICU patients.
4. To explore the association between elevated cortisol levels and length of ICU stay among critically ill patients.
5. To examine the relationship between the baseline serum cortisol levels and vasopressor requirements among the patients admitted into ICU
The study will be carried out in Lagos State University Teaching Hospital (LASUTH) where ethical approval has been obtained. All ICU patients above 18 years will be recruited for the study.
Patients on steroid therapy, or recent steroid exposure as well as pregnant patients will be excluded.
BAseline cortisol levels at admission and APACHE II scores will be compared.
The 21 day mortality will be measured.
The finding will contribute to prognostication in the ICU, hence may reduce financial burden of care in the face of medical futility thus reducing the cost of admissions and bed blockade/ occupancy.
OLADOKUN OLUWASEUN is a Lecturer I at the Department of Anasthesia
OLADOKUN has a Fellowship in Anaesthesia from National Postgraduate Medical College of Nigeria
